Santiago

Experiencia demostrada en Organic Synthesis.

Experiencia demostrada en Biochemical Assays.

Experiencia demostrada en Molecular Biology Techniques.

Coordinator of formalities and filing team for patent applications in Latin American countries., Advice Colombian and international applicants in the prosecution of patent applications in different countries., Generate and execute suitable and tailored strategies for overcoming requests from the Patents Offices from both technical and legal perspectives, considering the country and status of the application, relevance of the case for the applicant, among other variables., Executing prior art searches and reports, and drafting patent applications.

Designed, executed and optimized PCR set up for amplification and identification of wild-type bacterial isolates., Analyzed DNA sequences by paired and multi-sequence alignments., Identified species of the bacterial isolates as candidates for control of malaria.

Designed and executed the chemical process to furnish a library of new benzimidazole-derived medicinal leads., Analyzed samples for characterization and purity quantification by NMR, HPLC-MS and GC-MS., Designed and executed MIC, sterility and antibiotic strength assays to assess the antimicrobial activity of the synthetized molecules., Executed molecular biology assays (DNA extraction and restriction, transformation, DNA-EMSA) to study possible mechanisms of action., Postulated possible further experiments to determine mechanism of action of tested compounds.